Prostata is a natural history model of prostate cancer model which extends the model developed by Ruth Etzioni and colleagues at the Fred Hutchinson Cancer Research Center (FHCRC). This is a well ...
Nucleosomes are barriers to RNA Polymerase II (Pol II) transcribing along gene bodies in eukaryotes. We found that a fragile “tailless nucleosome” could be generated to resolve the Pol II pausing ...