Initially, cells are dissociated from liver tissues into single-cell suspensions using in vivo enzymatic perfusion or ex vivo digestion methods. The cells of interest are then enriched from the ...
Spatial transcriptomics is a cutting-edge technique that characterizes gene expression within sections of tissue, such as heart, skin or liver tissue. These snapshots provide insights into how spatial ...
This article explores how single-cell multiomics and spatial transcriptomics are illuminating early pregnancy, uncovering ...
Immune low-response states significantly impact the effectiveness of immunotherapy in cancer treatment. These states ...
Scientists at Duke-NUS Medical School have developed two powerful computational tools that could transform how researchers ...
"Transforming Biological Research and Personalized Medicine: Single-Cell Genomics and Proteomics Show Cellular Heterogeneity, Driving Advances in Disease Mechanisms, Drug Discovery, and Precision ...
A comprehensive review article titled “Bioinformatics perspectives on transcriptomics: A comprehensive review of bulk and single-cell RNA sequencing analyses,” published in Quantitative Biology, ...
For stem cells to differentiate into the appropriate cell-type, transcription factors (TFs) must be tailored to highly specific expression patterns of lineage-specific genes. Abnormalities in the ...
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